Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7163496 | 0.88 | — | — | |
| SCHEMBL4445541 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| Acetic Acid SCHEMBL2462664 | 0.80 | CA1 (0.41) | ALDH1A1LMNACA2CA1 | |
| SCHEMBL7163488 | 0.77 | — | — | |
| Acetic Acid SCHEMBL2466675 | 0.75 | CA1 (0.36) | CA1 | |
| SCHEMBL5726031 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNA | |
| SCHEMBL4450799 | 0.74 | SLC22A6 (0.31) | ALDH1A1LMNA | |
| Acetic Acid SCHEMBL2462585 | 0.74 | CA1 (0.35) | ALDH1A1LMNACA1 | |
| Acetic Acid SCHEMBL2465474 | 0.74 | CA1 (0.35) | ALDH1A1LMNACA1 | |
| Acetic Acid SCHEMBL2463875 | 0.74 | CA1 (0.35) | ALDH1A1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541564-B2 | Copolymerization of carbon monoxide and the olefinically unsaturated carried out in an aqueous medium in the presence of metal complexes, dispersant, organic hydroxy compound, wherein the soluble macromolecular host compound | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| US-20020198359-A1 | Priparation of copolymers of carbon monoxide and an olefinically unsaturated compound in an aqueous medium | BASF AKIENGESELLSCHAFT (DE) | 2002-12-26 | — | — | US | disclosed |