Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 4/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Karanjin SCHEMBL247164 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| Karanjonol SCHEMBL21828762 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| Pongapin SCHEMBL17554011 | 0.79 | CYP1A1 (1.00) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL29598759 | 0.77 | ABCG2 (0.64) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL8511950 | 0.76 | APP (0.74) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL31238064 | 0.76 | CYP1A1 (0.75) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL29993383 | 0.76 | ABCG2 (1.00) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL253523 | 0.76 | ABCG2 (1.00) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL4282126 | 0.76 | ABCG2 (0.69) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL7374619 | 0.76 | ABCG2 (0.69) | KDM4EALDH1A1CYP1A1CYP1B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |