Karanjin

Karanjin

SCHEMBL247164

COc1c(-c2ccccc2)oc2c(ccc3occc32)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 1.00
▸ ALDH1A1 P00352 5/20 1.00
▸ CYP1A1 P04798 4/20 1.00
▸ CYP1B1 Q16678 4/20 1.00
▸ CYP3A4 P08684 4/20 1.00
▸ HPGD P15428 4/20 1.00
▸ HSD17B10 Q99714 4/20 1.00
▸ MAPT P10636 4/20 1.00
▸ CYP2D6 P10635 2/20 1.00
▸ CYP2C9 P11712 2/20 1.00
▸ TSHR P16473 2/20 1.00
▸ CYP2C19 P33261 2/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ CYP1A2 P05177 3/20 0.71
▸ ABCG2 Q9UNQ0 9/20 0.67
▸ ABCC1 P33527 3/20 0.67
▸ MEN1 O00255 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ THRB P10828 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Karanjin SCHEMBL7164819 1.00 KDM4E (1.00) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
Karanjonol SCHEMBL21828762 0.80 KDM4E (0.71) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
Pongapin SCHEMBL17554011 0.79 CYP1A1 (1.00) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL29598759 0.77 ABCG2 (0.64) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL8511950 0.76 APP (0.74) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL31238064 0.76 CYP1A1 (0.75) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL29993383 0.76 ABCG2 (1.00) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL253523 0.76 ABCG2 (1.00) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL4282126 0.76 ABCG2 (0.69) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4
SCHEMBL7374619 0.76 ABCG2 (0.69) KDM4EALDH1A1CYP1A1CYP1B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 882 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12610971-B2 Pongamia compositions, methods of preparing and analyzing thereof, and uses thereof TerViva BioEnergy, Inc. (US) 2026-04-28 — — US claimed
US-20260076366-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS 0903608 B C LTD (CA) 2026-03-19 — — US claimed
US-20250367107-A1 SUNSCREEN COMPOSITION INCLUDING A SALICYLATE AND PONGAMIA PINNATA SEED EXTRACT EDGEWELL PERSONAL CARE BRANDS LLC (US) 2025-12-04 — — US claimed
US-20250089726-A1 BOTANICAL BASED BIO-STIMULANT, BIO-ACARICIDAL COMPOSITIONS KAY BEE BIO ORGANICS PVT LTD (IN) 2025-03-20 — — US claimed
CN-115068588-B Application of cytisine effective component in preparing HPV (human papillomavirus) resistant gel 江西康林药业有限公司 2025-03-18 — — CN claimed
US-20240415129-A1 BOTANICAL BASED BIO-INSECTICIDAL COMPOSITIONS FOR CONTROLLING PESTS AND IMPROVING THE PLANT PHYSIOLOGICAL PROCESS KAY BEE BIO ORGANICS PVT LTD (IN) 2024-12-19 — — US claimed
EP-4444870-A1 METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2024-10-16 — — EP claimed
WO-2024026464-A1 SUNSCREEN COMPOSITION INCLUDING A SALICYLATE AND PONGAMIA PINNATA SEED EXTRACT EDGEWELL PERSONAL CARE BRANDS, LLC (US) 2024-02-01 — — WO claimed
US-20230217944-A1 PONGAMIA OIL COMPOSITIONS, AND METHODS FOR PRODUCING AND USING THEREOF Terviva, Inc. (US) 2023-07-13 — — US claimed
WO-2023107477-A1 METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2023-06-15 — — WO claimed
CN-102462727-A Yulangsan general flavone and action of monomer component thereof in preparation of anti-tumor medicament INST MEDICINAL PLANT DEV CAMS 2012-05-23 — — CN claimed
CN-102372720-A Method for purifying high-content karanjin SUZHOU BAOZETANG MEDICAL TECH 2012-03-14 — — CN claimed
CN-102241686-A Preparation method of karanjin NANJING ZELANG AGRI DEV CO LTD 2011-11-16 — — CN claimed
CN-102133258-A Extracting and purifying process of pongamia pinnata flavonoids YI ZHU 2011-07-27 — — CN claimed
WO-2011027362-A2 A HERBAL ANTI-TERMITE FORMULATION KUMAR VISHAL (IN) 2011-03-10 — — WO claimed
WO-2008141074-A1 IDENTIFICATION OF COMPOUNDS THAT PROTECT AGAINST AMYLOID DISEASES SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2008-11-20 — — WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 — — US claimed
JP-2003504327-A — — 2003-02-04 — — JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 — — EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12610971-B2 Pongamia compositions, methods of preparing and analyzing thereof, and uses thereof DEK, DGKG, SRMS KDM4E 1254/4885ALDH1A1 3965/4885CYP1A1 2801/4885
US-20260076366-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS TACR3, GSTO1, TIAL1 KDM4E 3612/4885ALDH1A1 3336/4885CYP1A1 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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