Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810439 | 0.95 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL973763 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL4820813 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL4811916 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL5731717 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBMAPK1MAPT | |
| SCHEMBL4817444 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL4817033 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL4821137 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBHPGDMAPK1 | |
| SCHEMBL5622818 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBHPGDTSHR | |
| SCHEMBL6991189 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359150-A2 | A process and intermediates for the preparation of fungicidal 7-alkyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-05 | — | — | EP | disclosed |