Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165653 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL6990107 | 0.89 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL4811916 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL4820813 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL4810439 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL6996981 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL976567 | 0.85 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL4492293 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL6994541 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB | |
| SCHEMBL7000548 | 0.82 | KDM4E (0.42) | ALDH1A1KDM4ESMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054888-B1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2003-11-26 | — | — | EP | claimed |
| EP-1307200-A2 | SUBSTITUTED-TRIAZOLOPYRIMIDINES AS ANTICANCER AGENTS | Wyeth (US) | 2003-05-07 | — | — | EP | claimed |
| US-20020068744-A1 | Substituted-triazolopyrimidines as anticancer agents | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-06 | — | — | US | claimed |
| WO-2002002563-A2 | SUBSTITUTED-TRIAZOLOPYRIMIDINES AS ANTICANCER AGENTS | WYETH (US) | 2002-01-10 | — | — | WO | claimed |
| EP-1054888-A1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 2000-11-29 | — | — | EP | claimed |
| US-6020338-A | Fungicidal 7-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-02-01 | — | — | US | claimed |
| WO-1999041255-A1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 1999-08-19 | — | — | WO | claimed |
| US-8974806-B2 | Method for producing aqueous active substance compositions of active substances that are hardly soluble in water | BASF AKTIENGESELLSCHAFT (DE) | 2015-03-10 | — | — | US | disclosed |
| US-8741324-B2 | Liquid pesticide compositions | BASF SE (DE) | 2014-06-03 | — | — | US | disclosed |
| US-8728504-B2 | Process for solubilizing hydrophobic active ingredients in aqueous medium | BASF SE (DE) | 2014-05-20 | — | — | US | disclosed |
| US-8497230-B2 | Solid crop protection agents containing polyalkoxylate, method for their production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2013-07-30 | — | — | US | disclosed |
| US-20130123108-A1 | ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| EP-1763300-B1 | USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS | BASF SE (DE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2006015791-A2 | METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-16 | — | — | WO | disclosed |
| EP-1054888-B1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1359150-A2 | A process and intermediates for the preparation of fungicidal 7-alkyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-05 | — | — | EP | disclosed |
| US-20020068744-A1 | Substituted-triazolopyrimidines as anticancer agents | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-06 | — | — | US | disclosed |
| EP-1054888-A1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6020338-A | Fungicidal 7-alkyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1999041255-A1 | FUNGICIDAL 7-ALKYL-TRIAZOLOPYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068744-A1 | Substituted-triazolopyrimidines as anticancer agents | TUBB3, TUBA1C, TUBB1 | ALDH1A1 2231/4885KDM4E 3074/4885SMN1; SMN2 655/4885 |
| US-20130123108-A1 | ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER | NOS1, NOS3, NPSR1 | ALDH1A1 2770/4885KDM4E 4272/4885SMN1; SMN2 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.