Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126648 | 0.91 | ERAP1 (0.51) | ERAP1ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL7120589 | 0.85 | ESR2 (0.53) | ERAP1KCNA3ESR1ESR2ALDH1A1 | |
| SCHEMBL7117111 | 0.85 | ERAP1 (0.49) | ERAP1PTGS1PTGS2ESR1ESR2 | |
| SCHEMBL7117105 | 0.81 | CYP19A1 (0.52) | ERAP1PTGS2ALDH1A1HPGDMAPT | |
| SCHEMBL7124530 | 0.81 | C1R (0.46) | ALDH1A1HPGDTP53NPC1RAB9A | |
| SCHEMBL7115934 | 0.80 | ESR1 (0.47) | ERAP1ESR1ESR2NPC1KMT2A | |
| SCHEMBL31675804 | 0.80 | ERAP1 (0.62) | ERAP1ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL7164709 | 0.80 | ERAP1 (0.62) | ERAP1ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL7125137 | 0.79 | CYP19A1 (0.57) | ALDH1A1HPGDTP53MAPTNPC1 | |
| SCHEMBL7123286 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |