SCHEMBL716608

SCHEMBL716608

Fc1ccc(-c2nc3c(nc2-c2ccc(F)cc2)CCCC3)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.52
MAPK14 Q16539 3/20 0.44
MAPK10 P53779 1/20 0.44
HTR2A P28223 10/20 0.42
HTR2C P28335 10/20 0.42
HTR2B P41595 10/20 0.42
GRM5 P41594 1/20 0.41
GRM1 Q13255 1/20 0.41
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HRH2 P25021 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
ADORA2A P29274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717382 0.77 KDM4E (0.47) KMT2AMAPK10KDM4ENPC1ALDH1A1
SCHEMBL9558689 0.75 HTR2A (0.47) HTR2AHTR2CHTR2BKDM4ENPC1
SCHEMBL9558713 0.74 HTR2A (0.46) HTR2AHTR2CHTR2BKDM4ENPC1
SCHEMBL10444960 0.74 HRH3 (0.62) KMT2AHTR2AHTR2CHTR2BKDM4E
SCHEMBL15116212 0.73 MAPK14 (0.42) MAPK14MAPK10HTR2AHTR2CHTR2B
SCHEMBL183610 0.71 HTR2A (0.75) HTR2AHTR2CHTR2BKDM4ENPC1
SCHEMBL9558730 0.71 KDM4E (0.48) MAPK14HTR2AHTR2CHTR2BKDM4E
SCHEMBL3391196 0.71 HTR2A (0.36) KMT2AMAPK14HTR2AHTR2CHTR2B
SCHEMBL3869454 0.71 KMT2A (0.41) KMT2AMAPK14HTR2AHTR2CGRM5
SCHEMBL25220187 0.70 SMPD3 (0.49) KMT2AMAPK14KDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866321-B1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING DEVICE AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LAB (JP) 2014-04-23 EP disclosed
US-8389132-B2 Organometallic complex, and light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
US-8389132-B2 Organometallic complex, and light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
US-8389132-B2 Organometallic complex, and light-emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
US-20120049727-A1 Organometallic Complex, and Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-01 US disclosed
US-20120049727-A1 Organometallic Complex, and Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-01 US disclosed
US-20120049727-A1 Organometallic Complex, and Light-Emitting Device and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-01 US disclosed
US-8053974-B2 Organometallic complex, and light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-11-08 US disclosed
US-8053974-B2 Organometallic complex, and light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-11-08 US disclosed
US-8053974-B2 Organometallic complex, and light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-11-08 US disclosed
US-20090033209-A1 Organometallic Complex, And Light Emitting Device And Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-02-05 US disclosed
US-20090033209-A1 Organometallic Complex, And Light Emitting Device And Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-02-05 US disclosed
US-20090033209-A1 Organometallic Complex, And Light Emitting Device And Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-02-05 US disclosed
EP-1866321-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING DEVICE AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-12-19 EP disclosed
WO-2006104177-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING DEVICE AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120049727-A1 Organometallic Complex, and Light-Emitting Device and Electronic Appliance Using the Same AFF1, AP3M1, AP2M1 KMT2A 515/4885MAPK14 4320/4885MAPK10 3411/4885
US-20090033209-A1 Organometallic Complex, And Light Emitting Device And Electronic Appliance Using the Same AFF1, AP3M1, AP2M1 KMT2A 534/4885MAPK14 4521/4885MAPK10 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.