Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703170 | 0.82 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL6202232 | 0.78 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL16908675 | 0.74 | CYP2C19 (0.42) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL17757012 | 0.74 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL9785440 | 0.74 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL5420620 | 0.74 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL16908693 | 0.74 | CYP2C19 (0.42) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL5936799 | 0.72 | GRIK1 (0.35) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL8731754 | 0.71 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL7596861 | 0.71 | GRIK1 (0.41) | GRIK1GRIK2CYP2C19CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | claimed |
| US-6599721-B2 | Chemical intermediates; hydrolysis using hydrolases | LONZA AG (CH) | 2003-07-29 | — | — | US | disclosed |
| US-6599721-B2 | Chemical intermediates; hydrolysis using hydrolases | LONZA AG (CH) | 2003-07-29 | — | — | US | disclosed |
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | disclosed |
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | disclosed |
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | disclosed |