Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202232 | 0.79 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL3153113 | 0.78 | GRIK1 (0.36) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL28221463 | 0.77 | CYP2D6 (0.34) | CYP2C19 | |
| SCHEMBL17757012 | 0.75 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL9785440 | 0.75 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL5420620 | 0.75 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL5936759 | 0.74 | CHRM1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL7600439 | 0.73 | GRIK1 (0.33) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL8731754 | 0.72 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL7166143 | 0.72 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2006-10-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | MALT1, HDAC11, GABRA6 | GRIK1 144/4885GRIK2 90/4885CYP2C19 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.