Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856861 | 0.84 | GRIK1 (0.32) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL6455497 | 0.80 | GRIK1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL3453903 | 0.80 | ALDH1A1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL5936799 | 0.79 | GRIK1 (0.35) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL7166143 | 0.78 | GRIK1 (0.37) | GRIK1GRIK2CYP2C19CPA1 | |
| SCHEMBL29028868 | 0.78 | ABCC4 (0.33) | ABCC4MAPT | |
| SCHEMBL16908675 | 0.77 | CYP2C19 (0.42) | GRIK1GRIK2CYP2C19CPA1ABCC4 | |
| SCHEMBL16908693 | 0.77 | CYP2C19 (0.42) | GRIK1GRIK2CYP2C19CPA1ABCC4 | |
| SCHEMBL17757012 | 0.77 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1ABCC4 | |
| SCHEMBL9785440 | 0.77 | GRIK1 (0.39) | GRIK1GRIK2CYP2C19CPA1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1155138-B1 | METHOD FOR PREPARING OPTICALLY ACTIVE 3,3,3-TRIFLUOROMETHYL-2-ALKYL PROPIONIC ACID DERIVATIVES | LONZA AG (CH) | 2005-01-05 | — | — | EP | claimed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | claimed |
| US-6599721-B2 | Chemical intermediates; hydrolysis using hydrolases | LONZA AG (CH) | 2003-07-29 | — | — | US | claimed |
| CN-116171154-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-6599721-B2 | Chemical intermediates; hydrolysis using hydrolases | LONZA AG (CH) | 2003-07-29 | — | — | US | disclosed |