SCHEMBL7166369

SCHEMBL7166369

C[S+](C)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 5/20 0.45
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
CA2 P00918 3/20 0.33
NOS1 P29475 2/20 0.33
CA1 P00915 2/20 0.33
TSHR P16473 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TAAR1 Q96RJ0 3/20 0.32
HTR2A P28223 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802017 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL2575115 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL3201605 0.73 CYP2A6 (0.57) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL5702435 0.71 ACHE (0.53) CYP2A6ALDH1A1TDP1CA2CA1
SCHEMBL18508 0.71
SCHEMBL6117653 0.69 ACHE (0.45) CA2NOS1CA1CES2CES1
SCHEMBL9245852 0.69 CA1 (0.32) CA2CA1
Fluoride Ion SCHEMBL11660219 0.69 ACHE (0.50) CYP2A6ALDH1A1TDP1CA2CA1
Hydrochloric Acid SCHEMBL11620241 0.69 ACHE (0.50) CYP2A6ALDH1A1TDP1CA2CA1
SCHEMBL245789 0.69 CYP3A4 (0.50) ALDH1A1ALOX15MAPK1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066303-B1 TRANSITION METAL COMPOUND CONTAINING CATIONIC GROUPS WHICH IS USED AS AN OLEFIN POLYMERIZATION CATALYST COMPONENT BASELL POLYOLEFINE GMBH (DE) 2003-09-10 EP claimed
US-6583238-B1 Polypropylene having extraordinarily high stereospecificity and regiospecificity; BASELL POLYOLEFINE GMBH (DE) 2003-06-24 US claimed
US-6552210-B1 Metallocenes which can be firmly fixed to support; gas phase polymerization TARGOR GMBH (DE) 2003-04-22 US claimed
EP-1066330-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF, AND THE UTILIZATION THEREOF FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2002-02-06 EP claimed
CN-109554122-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2022-03-01 CN disclosed
US-6583238-B1 Polypropylene having extraordinarily high stereospecificity and regiospecificity; BASELL POLYOLEFINE GMBH (DE) 2003-06-24 US disclosed
US-6552210-B1 Metallocenes which can be firmly fixed to support; gas phase polymerization TARGOR GMBH (DE) 2003-04-22 US disclosed