Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | TK2 | O00142 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166600 | 1.00 | TK1 (0.61) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL7173806 | 0.97 | TK1 (0.60) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL7173802 | 0.97 | TK1 (0.60) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL7168837 | 0.96 | TK1 (0.59) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL7168840 | 0.96 | TK1 (0.59) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL4264413 | 0.94 | TK1 (0.64) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL4264417 | 0.94 | TK1 (0.64) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL3931463 | 0.92 | TK1 (0.63) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL21585108 | 0.92 | TK1 (0.63) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL3931456 | 0.92 | TK1 (0.63) | TK1LMNASMN1; SMN2ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573247-B1 | Prophylaxis or treatment of varicella-zoster virus or cytomegalo virus infections | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |
| EP-0980377-B1 | ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES | UNIV CARDIFF (GB) | 2002-07-31 | — | — | EP | disclosed |
| EP-0980377-A1 | ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES | University College Cardiff Consultants Limited (GB) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049177-A1 | ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1998-11-05 | — | — | WO | disclosed |