Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16398951 | 0.81 | MAPT (0.42) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| Bromide SCHEMBL7166810 | 0.80 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL28448933 | 0.78 | CYP3A4 (0.47) | CYP2D6MAPTCYP3A4LMNANAAA | |
| Bromide SCHEMBL1996581 | 0.77 | KMT2A (0.49) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| SCHEMBL12566371 | 0.76 | MAPT (0.51) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| Bromide SCHEMBL2868130 | 0.74 | KMT2A (0.75) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| Bromide SCHEMBL6024741 | 0.74 | KMT2A (0.75) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| Bromide SCHEMBL7141677 | 0.74 | KMT2A (0.75) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| Bromide SCHEMBL6224118 | 0.74 | KMT2A (0.75) | CYP2D6MAPTMEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL11436662 | 0.74 | KMT2A (0.47) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569361-B1 | Polycondensation or polyaddition of electrochromic monomers are used in devices for variable transparency | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-27 | — | — | US | disclosed |