Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373398 | 0.86 | HPGD (0.37) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL713098 | 0.79 | HPGD (0.37) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL373242 | 0.76 | HPGD (0.37) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL373658 | 0.76 | MYC (0.37) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL373796 | 0.74 | MAPT (0.43) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL373515 | 0.72 | MAPT (0.39) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL28553324 | 0.72 | LMNA (0.48) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL373541 | 0.71 | HPGD (0.37) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL16594817 | 0.70 | PPARG (0.39) | MAPTHPGDLMNAKDM4ECYP3A4 | |
| SCHEMBL373543 | 0.70 | HPGD (0.41) | MAPTHPGDLMNAKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638991-B2 | Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength | MENICON CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20020198280-A1 | Material for ocular lens | MENICON CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6027745-A | Process for producing controlled drug-release contact lens, and controlled drug-release contact lens thereby produced | MENICON CO., LTD. (JP) | 2000-02-22 | — | — | US | disclosed |