SCHEMBL713098

SCHEMBL713098

C=C(C)C(=O)ON(CC)c1ccccc1N=Nc1cc(C(=O)c2ccccc2)c(O)cc1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ELANE P08246 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 2/20 0.35
CYP1A2 P05177 1/20 0.35
PGR P06401 1/20 0.35
CYP2D6 P10635 1/20 0.35
SLC6A2 P23975 1/20 0.35
PDE4A P27815 1/20 0.35
CYP2C19 P33261 1/20 0.35
HRH1 P35367 1/20 0.35
HTT P42858 1/20 0.35
SLC6A3 Q01959 1/20 0.35
PDE4D Q08499 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373381 0.87 LMNA (0.36) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL373696 0.85 MAPT (0.35) HPGDLMNAMAPTKDM4ERECQL
SCHEMBL373242 0.83 HPGD (0.37) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL373398 0.83 HPGD (0.37) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL7167202 0.79 MAPT (0.39) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL373796 0.78 MAPT (0.43) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL373515 0.76 MAPT (0.39) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL373541 0.74 HPGD (0.37) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL373548 0.74 LMNA (0.36) HPGDLMNAMAPTKDM4ECYP3A4
SCHEMBL7178326 0.74 HPGD (0.41) HPGDLMNAMAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330161-B1 DYE COMPOSITION FOR OPHTHALMIC LENS, METHOD FOR PRODUCING COLORED OPHTHALMIC LENS USING THE SAME AND COLORED OPHTHALMIC LENS MENICON CO LTD (JP) 2017-01-25 EP disclosed
US-8927618-B2 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2015-01-06 US disclosed
EP-2180366-B1 SILICONE-CONTAINING OCULAR LENS MATERIAL WITH HIGH SAFETY AND PREPARING METHOD THEREOF MENICON CO LTD (JP) 2013-09-25 EP disclosed
EP-1696257-B1 CONTACT LENS MATERIAL MENICON CO LTD (JP) 2012-11-21 EP disclosed
US-8124668-B2 Silicone-containing ocular lens material with high safety and preparing method thereof MENICON CO., LTD. (JP) 2012-02-28 US disclosed
EP-2330161-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens Menicon Co., Ltd. (JP) 2011-06-08 EP disclosed
US-20110116034-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2011-05-19 US disclosed
EP-1750157-B1 CONTACT LENS MENICON CO LTD (JP) 2010-10-13 EP disclosed
EP-2180366-A1 Silicone-containing ocular lens material with high safety and preparing method thereof MENICON CO., LTD. (JP) 2010-04-28 EP disclosed
US-20090247662-A1 Contact Lens Material MATSUMOTO MASAHIRO 2009-10-01 US disclosed
EP-1197782-B1 MATERIAL FOR OCULAR LENS MENICON CO LTD (JP) 2004-06-02 EP disclosed
US-20040039077-A1 Ocular lens material MENICON CO., LTD. 2004-02-26 US disclosed
EP-1197782-A1 MATERIAL FOR OCULAR LENS MENICON CO., LTD. (JP) 2002-04-17 EP disclosed
US-6329445-B1 Ocular lens material MENICON CO., LTD (JP) 2001-12-11 US disclosed
EP-1033590-A2 Ocular lens material Menicon Co., Ltd. (JP) 2000-09-06 EP disclosed
EP-0947856-A2 Ocular lens material Menicon Co., Ltd. (JP) 1999-10-06 EP disclosed
US-5416132-A Acrylamide modified acrylate modified polysiloxanes MENICON CO., LTD. (JP) 1995-05-16 US disclosed
EP-0381005-B1 Ocular lens material MENICON CO LTD (JP) 1995-01-11 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
EP-0381005-A2 Ocular lens material Menicon Co., Ltd. (JP) 1990-08-08 EP disclosed