Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167365 | 1.00 | TSHR (0.43) | TSHRCASP1LMNA | |
| SCHEMBL8432322 | 0.97 | TSHR (0.48) | TSHRCASP1LMNA | |
| SCHEMBL9965954 | 0.77 | SIGMAR1 (0.33) | — | |
| SCHEMBL1353096 | 0.75 | TSHR (0.40) | TSHRCASP1LMNA | |
| SCHEMBL1353098 | 0.75 | TSHR (0.40) | TSHRCASP1LMNA | |
| SCHEMBL9963291 | 0.72 | CHRNA7 (0.52) | — | |
| SCHEMBL11486086 | 0.70 | TSHR (0.36) | TSHRCASP1LMNA | |
| SCHEMBL11165836 | 0.70 | TSHR (0.36) | TSHRCASP1LMNA | |
| SCHEMBL11459056 | 0.70 | TSHR (0.36) | TSHRCASP1LMNA | |
| SCHEMBL11165834 | 0.70 | TSHR (0.36) | TSHRCASP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229072-A1 | Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binning agents | BULLOCK WILLIAM H (US) | 2003-12-11 | — | — | US | disclosed |
| EP-1317456-A2 | CYCLIC AND ACYCLIC AMIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020526-A2 | CYCLIC AND ACYCLIC AMIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229072-A1 | Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binning agents | PGR, PGRMC1, PGRMC2 | TSHR 108/4885CASP1 4559/4885LMNA 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.