Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3181294 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3792335 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8099653 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5084888 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5085298 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27884199 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Decyltriphenylphosphonium SCHEMBL5087261 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5088181 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2415697 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5085239 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220064524-A1 | STABILIZED PEROVSKITE QUANTUM DOT MATERIAL | QUANTUM ADVANCED SOLUTIONS LIMITED (GB) | 2022-03-03 | — | — | US | claimed |
| CN-112457191-A | (meth) acrylic acid ester compound | 上海墨之炫科技有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112251062-A | Environment-friendly coating for adsorbing formaldehyde | 南京市安尔康环境科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-109401496-A | A kind of environmental friendly indoor purification coating and preparation method thereof | 合肥隆扬环保科技有限公司 | 2019-03-01 | — | — | CN | claimed |
| EP-3435766-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | Dentsply Sirona Inc. (US) | 2019-02-06 | — | — | EP | claimed |
| WO-2017173294-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC. (US) | 2017-10-05 | — | — | WO | claimed |
| US-20170280725-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | DENTSPLY SIRONA INC (US) | 2017-10-05 | — | — | US | claimed |
| CN-107151933-A | A kind of low dissolved salt based on Integration Data Model cleans the preparation method of paper pulp | 沙良宝 | 2017-09-12 | — | — | CN | claimed |
| CN-107119479-A | A kind of low dissolved salt cleaning paper pulp and preparation method thereof | 沙良宝 | 2017-09-01 | — | — | CN | claimed |
| CN-106669633-A | Adsorption preparation for wastewater treatment and preparation method thereof | 中国环境科学研究院 | 2017-05-17 | — | — | CN | claimed |
| CN-106342961-A | Disinfection powder of landscape fish pond water and preparation method of disinfection powder | 怀远县渔业科技发展有限责任公司 | 2017-01-25 | — | — | CN | claimed |
| CN-104140731-B | A kind of preparation method of aqueous flame retardant coating | DUAN XIAONING (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-104031514-B | The preparation method of the core-shell type aqueous acrylic resin coating of a kind of flame retardant resistance | DUAN BAORONG (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-105211136-A | A kind of landscape fishpond water sterilization powder and preparation method thereof | BENGBU LONGDA AGRICULTURE SPECIALIZED COOPERATIVE | 2016-01-06 | — | — | CN | claimed |
| CN-105145685-A | Sterilizing extract for water in ornamental fish ponds and preparation method thereof | BENGBU LONGDA AGRICULTURE PROFESSIONAL COOPERATIVES | 2015-12-16 | — | — | CN | claimed |
| CN-104140731-A | Preparing method of flame-retardant water-borne coating | DUAN XIAONING | 2014-11-12 | — | — | CN | claimed |
| CN-104031514-A | Preparation method of flame resistance core-shell type aqueous acrylic ester resin coating | DUAN BAORONG | 2014-09-10 | — | — | CN | claimed |
| CN-101926358-B | Quaternary phosphonium salt pillared layered zirconium phosphate material, and preparation method and application thereof | UNIV JINAN | 2014-01-29 | — | — | CN | claimed |
| CN-101926358-A | Quaternary phosphonium salt pillared layered zirconium phosphate material, and preparation method and application thereof | UNIV JINAN | 2010-12-29 | — | — | CN | claimed |
| US-3997705-A | Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170280725-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND INTERRUPTION OF BIOFILM FORMATION | FGB, TFPI, F12 | BDKRB2 3244/4885HIF1A 797/4885TRAP1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.