Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.69 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165844 | 0.94 | MTNR1A (0.70) | MTNR1AMTNR1BNPC1RAB9AEPHX2 | |
| SCHEMBL7168613 | 0.88 | MTNR1A (0.60) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL7171025 | 0.87 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL7169122 | 0.84 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL7173385 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL8116804 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7165829 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL8133068 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL422827 | 0.79 | L3MBTL1 (0.68) | MTNR1AMTNR1BNPC1RAB9AEPHX2 | |
| SCHEMBL7171634 | 0.78 | MTNR1A (0.59) | MTNR1AMTNR1BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569894-B1 | Such as N-(3-(2-(4-phenylbutyl)-2,3-dihydrobenzofuran-4-yl)propyl)acetamide for treating circadian rhythm-related disorders | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-27 | — | — | US | disclosed |