Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697829 | 1.00 | KMT2A (0.38) | KMT2AL3MBTL1SYKBCHEACHE | |
| SCHEMBL6697354 | 0.90 | SYK (0.41) | KMT2AL3MBTL1SYKCTSLALDH1A1 | |
| SCHEMBL6787767 | 0.90 | KMT2A (0.40) | KMT2AL3MBTL1SYKBCHEACHE | |
| SCHEMBL6696742 | 0.89 | KMT2A (0.42) | KMT2AL3MBTL1SYKCTSLGPR119 | |
| SCHEMBL6693641 | 0.88 | KMT2A (0.42) | KMT2AL3MBTL1SYKGPR119ACE | |
| SCHEMBL6704197 | 0.82 | KMT2A (0.42) | KMT2AL3MBTL1SYKCTSLCPB1 | |
| SCHEMBL7170460 | 0.81 | CPB1 (0.40) | KMT2ACTSLACEALDH1A1CPB1 | |
| SCHEMBL6697066 | 0.81 | KMT2A (0.41) | KMT2AL3MBTL1SYKCTSLGPR119 | |
| SCHEMBL6700665 | 0.81 | KMT2A (0.41) | KMT2AL3MBTL1SYKCTSLGPR119 | |
| SCHEMBL6693629 | 0.81 | KMT2A (0.41) | KMT2AL3MBTL1SYKGPR119ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358154-A2 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF NEURAMINIDASES | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2001028996-A2 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-26 | — | — | WO | disclosed |