Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037936 | 0.84 | KMT2A (0.45) | ADORA3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3059808 | 0.79 | ADORA2B (0.55) | ADORA2AADORA1ADORA3ADORA2BNPC1 | |
| SCHEMBL3051217 | 0.79 | MAPT (0.46) | ADORA2AADORA1ADORA3ADORA2BL3MBTL1 | |
| SCHEMBL3047796 | 0.78 | CHRM4 (0.48) | ADORA3L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3051225 | 0.78 | MAPT (0.42) | ADORA2AADORA1ADORA3ADORA2BL3MBTL1 | |
| SCHEMBL3045403 | 0.77 | ADORA3 (0.48) | ADORA2AADORA1ADORA3ADORA2BMEN1 | |
| SCHEMBL3057647 | 0.77 | CYP19A1 (0.45) | ADORA3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3053017 | 0.76 | CYP19A1 (0.49) | L3MBTL1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3051788 | 0.74 | AR (0.54) | ADORA2AADORA1ADORA3ADORA2BNPC1 | |
| SCHEMBL24348855 | 0.74 | ADORA2A (0.90) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303272-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001097786-A2 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-12-27 | — | — | WO | disclosed |