Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.63 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | HTR2C | P28335 | 4/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.63 |
| ▸ | HRH1 | P35367 | 4/20 | 0.63 |
| ▸ | DRD3 | P35462 | 4/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | GHSR | Q92847 | 3/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172308 | 0.87 | HTR2A (0.54) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL7168069 | 0.85 | MTNR1A (0.46) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL8195707 | 0.81 | HTR2A (0.70) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL4669145 | 0.80 | CYP3A4 (0.65) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL7168599 | 0.80 | HTR2A (0.68) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL6963908 | 0.79 | HTR2A (0.71) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL14698925 | 0.79 | MEN1 (0.66) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL31256054 | 0.79 | HTR2A (0.71) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL764371 | 0.79 | HTR2A (0.57) | SLC6A2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL14707047 | 0.78 | HTR2A (0.74) | SLC6A2CHRM1DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |