Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | NPY1R | P25929 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPY2R | P49146 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926077 | 0.91 | SLC29A1 (0.66) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL28894286 | 0.90 | SLC29A1 (0.65) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL155837 | 0.89 | SLC29A1 (0.75) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL155836 | 0.89 | SLC29A1 (0.75) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL28821444 | 0.88 | SLC29A1 (0.63) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL8708994 | 0.87 | SLC29A1 (0.69) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL8709002 | 0.87 | SLC29A1 (0.69) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL5252809 | 0.87 | SLC29A1 (0.70) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL5252821 | 0.87 | SLC29A1 (0.70) | SLC29A1ADORA1LMNAALDH1A1GLA | |
| SCHEMBL6382045 | 0.87 | TSHR (0.66) | SLC29A1ADORA1PMP22SMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209440-B2 | T cell balance gene expression, compositions of matters and methods of use thereof | THE BROAD INSTITUTE, INC. | 2021-12-28 | — | — | US | disclosed |
| US-20160377631-A1 | T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2016-12-29 | — | — | US | disclosed |
| CN-1671716-A | Method of treating ischemia reperfusion injury using adenosine receptor antagonists | BIOGEN IDEC INC (US) | 2005-09-21 | — | — | CN | disclosed |
| US-6586413-B2 | Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-07-01 | — | — | US | disclosed |
| US-6211165-B1 | GENE EXPRESSION; BINARY CONJUGATES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-04-03 | — | — | US | disclosed |