SCHEMBL28894286

SCHEMBL28894286

NC(=O)NNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 4/20 0.65
ADORA3 P0DMS8 3/20 0.64
ADORA1 P30542 3/20 0.64
MAPK1 P28482 2/20 0.64
ADORA2A P29274 2/20 0.64
ADORA2B P29275 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
DPP4 P27487 1/20 0.64
MEN1 O00255 1/20 0.64
SLC28A1 O00337 1/20 0.64
MAP3K7 O43318 1/20 0.64
SLC28A2 O43868 1/20 0.64
GAPDH P04406 1/20 0.64
STAT6 P42226 1/20 0.64
PI4KA P42356 1/20 0.64
KMT2A Q03164 1/20 0.64
PI4K2B Q8TCG2 1/20 0.64
DOT1L Q8TEK3 1/20 0.64
PI4K2A Q9BTU6 1/20 0.64
SLC28A3 Q9HAS3 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7168674 0.90 SLC29A1 (0.67) SLC29A1ADORA3ADORA1SMN1; SMN2LMNA
SCHEMBL28477260 0.89 ADORA2A (0.67) SLC29A1ADORA3ADORA1MAPK1ADORA2A
SCHEMBL926077 0.89 SLC29A1 (0.66) SLC29A1ADORA3ADORA1SMN1; SMN2LMNA
SCHEMBL5252821 0.87 SLC29A1 (0.70) SLC29A1ADORA3ADORA1MAPK1ADORA2A
SCHEMBL5252809 0.87 SLC29A1 (0.70) SLC29A1ADORA3ADORA1MAPK1ADORA2A
SCHEMBL6382045 0.87 TSHR (0.66) SLC29A1ADORA3ADORA1ADORA2AADORA2B
SCHEMBL28821444 0.86 SLC29A1 (0.63) SLC29A1ADORA3ADORA1SMN1; SMN2LMNA
SCHEMBL28659436 0.86 SLC29A1 (0.58) SLC29A1TSHRNFKB1
SCHEMBL28659434 0.86 SLC29A1 (0.58) SLC29A1TSHRNFKB1
SCHEMBL29501846 0.85 LMNA (0.69) SLC29A1ADORA3ADORA1MAPK1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115389756-B Detection kit for predicting risk of atrial fibrillation and application thereof 首都医科大学附属北京安贞医院 2023-02-17 CN disclosed
CN-115389756-A Detection kit for predicting risk of atrial fibrillation and application thereof 首都医科大学附属北京安贞医院 2022-11-25 CN disclosed