SCHEMBL926077

SCHEMBL926077

CCC(=O)NNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.66
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
GLA P06280 1/20 0.63
PMP22 Q01453 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
ADORA1 P30542 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7168674 0.91 SLC29A1 (0.67) SLC29A1ALDH1A1LMNAGLAPMP22
SCHEMBL31307310 0.91 SLC29A1 (0.67) SLC29A1
SCHEMBL28821444 0.89 SLC29A1 (0.63) SLC29A1ALDH1A1LMNAGLAPMP22
SCHEMBL28894286 0.89 SLC29A1 (0.65) SLC29A1ALDH1A1LMNAGLAPMP22
SCHEMBL6382045 0.88 TSHR (0.66) SLC29A1PMP22SMN1; SMN2ADORA3ADORA1
SCHEMBL31395324 0.86 SLC29A1 (0.70) SLC29A1ALDH1A1LMNAGLAPMP22
SCHEMBL8708994 0.86 SLC29A1 (0.69) SLC29A1ALDH1A1LMNAGLAPMP22
SCHEMBL8709002 0.86 SLC29A1 (0.69) SLC29A1ALDH1A1LMNAGLAPMP22
SCHEMBL927700 0.85 ADORA1 (0.69) ADORA3ADORA1
SCHEMBL6474066 0.85 SLC29A1 (0.68) SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240358663-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-10-31 US claimed
US-20190160029-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-05-30 US claimed
WO-2017192553-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2017-11-09 WO claimed
EP-2204154-B1 Association of monosaccharides and adenosine and its cosmetic use ORÉAL L (FR) 2016-10-12 EP claimed
US-20110189255-A1 DRUG-ELUTING STENTS FOR ADENOSINE RECEPTOR MODULATION PURDUE RESEARCH FOUNDATION 2011-08-04 US claimed
US-7991601-B2 Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same DUKE UNIVERSITY (US) 2011-08-02 US claimed
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF L'OREAL (FR) 2010-07-01 US claimed
US-7691969-B2 Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same DUKE UNIVERSITY (US) 2010-04-06 US claimed
US-20080160636-A1 Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same DUKE UNIVERSITY (US) 2008-07-03 US claimed
EP-1846578-A2 METHODS OF IDENTIFYING GENES WHICH MODULATE MYELINATION Elan Pharmaceuticals Inc. (US) 2007-10-24 EP claimed
US-7235649-B2 Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same DUKE UNIVERSITY (US) 2007-06-26 US claimed
EP-1424064-B1 Use of adenosin or an adenosin analog to smooth out fine lines OREAL (FR) 2007-06-06 EP claimed
EP-1168912-B1 ORGAN ARREST, PROTECTION AND PRESERVATION HIBERNATION THERAPEUTICS LTD (AU) 2007-05-09 EP claimed
WO-2006086761-A2 METHODS OF IDENTIFYING GENES WHICH MODULATE MYELINATION ELAN PHARMACEUTICALS, INC. (US) 2006-08-17 WO claimed
US-20060183147-A1 Methods of identifying genes which modulate myelination ELAN PHARMACEUTICALS, INC. 2006-08-17 US claimed
EP-1325335-B1 METHODS FOR DIAGNOSING AND TREATING HUNTINGTON'S DISEASE UNIV DEGLI STUDI MILANO (IT) 2006-04-12 EP claimed
US-20040146474-A1 Method for softening lines and relaxing the skin with adenosine and adenosine analogues L'OREAL (FR) 2004-07-29 US claimed
US-20250387397-A1 SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE MERCK SHARP & DOHME LLC (US) 2025-12-25 US disclosed
EP-0544444-A1 Processes for the preparation f substituted triazolo 1,5-a 1,3,5 triazines ZENECA LIMITED (GB) 1993-06-02 EP disclosed
EP-0415456-A2 Xanthine compounds KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160636-A1 Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same HSPA1A, HSPA4L, HSPA4 SLC29A1 114/4885ALDH1A1 3226/4885LMNA 1412/4885
US-20240358663-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION VASP, MYLK, EDNRB SLC29A1 2418/4885ALDH1A1 2696/4885LMNA 781/4885
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF ADORA2A, ADORA1, ADORA3 SLC29A1 227/4885ALDH1A1 524/4885LMNA 2948/4885
US-20190160029-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION VASP, MYLK, EDNRB SLC29A1 2418/4885ALDH1A1 2696/4885LMNA 781/4885
US-20250387397-A1 SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE ADORA2A, ADORA2B, ADORA1 SLC29A1 124/4885ALDH1A1 291/4885LMNA 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.