Diphenylacetylene

Diphenylacetylene

SCHEMBL7168945

C(#Cc1ccccc1)c1ccccc1.O=C(O)c1ccccc1-c1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 2/20 0.56
BCAT2 O15382 1/20 0.55
FABP3 P05413 1/20 0.51
FABP4 P15090 1/20 0.51
FABP5 Q01469 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CHRNB2 P17787 2/20 0.49
CHRNB4 P30926 2/20 0.49
CHRNA3 P32297 2/20 0.49
CHRNA4 P43681 2/20 0.49
ALDH1A1 P00352 1/20 0.48
ALOX15 P16050 1/20 0.48
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
APP P05067 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133057 0.88 HNF4A (0.69) HNF4ABCAT2FABP3FABP4FABP5
Benzene SCHEMBL1403559 0.88 HNF4A (0.69) HNF4ABCAT2FABP3FABP4FABP5
Benzene SCHEMBL28480917 0.88 HNF4A (0.69) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL26624744 0.88 HNF4A (0.69) HNF4ABCAT2FABP3FABP4FABP5
Fluoride SCHEMBL11030268 0.86 HNF4A (0.67) HNF4ABCAT2FABP3FABP4FABP5
Biphenyl SCHEMBL9292498 0.86 HNF4A (0.67) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL7407371 0.86 HNF4A (0.73) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL17371707 0.86 HNF4A (0.67) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL8615784 0.86 HNF4A (0.67) HNF4ABCAT2FABP3FABP4FABP5
SCHEMBL8872993 0.86 HNF4A (0.67) HNF4ABCAT2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569504-B1 Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) DISPLAYTECH, INC. 2003-05-27 US disclosed
US-6139771-A USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS DISPLAYTECH, INC. (US) 2000-10-31 US disclosed