Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198080 | 0.84 | NISCH (0.30) | NISCH | |
| SCHEMBL3199427 | 0.78 | MAPT (0.37) | NISCH | |
| Hydrochloric Acid SCHEMBL7165108 | 0.76 | SALL4 (0.31) | NISCH | |
| Hydrochloric Acid SCHEMBL7169500 | 0.76 | SALL4 (0.31) | NISCH | |
| SCHEMBL7148640 | 0.75 | TRIM24 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28815114 | 0.70 | MAPT (0.38) | NISCH | |
| SCHEMBL9059241 | 0.69 | MAPT (0.37) | — | |
| Bromide SCHEMBL28815167 | 0.68 | MAPT (0.38) | — | |
| Iodide SCHEMBL28815180 | 0.68 | MAPT (0.38) | — | |
| Hydrochloric Acid SCHEMBL8077847 | 0.66 | MAPT (0.37) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153032-B1 | BIMETALLIC METALLOCENE CATALYST FOR ISOTACTIC POLYPROPYLENE POLYMERISATION | ATOFINA RES (BE) | 2003-04-02 | — | — | EP | disclosed |
| US-20020133034-A1 | Polyolefin production | RAZAVI ABBAS (BE) | 2002-09-19 | — | — | US | disclosed |
| US-20020120161-A1 | Polyolefin production | RAZAVI ABBAS (BE) | 2002-08-29 | — | — | US | disclosed |
| US-6407273-B1 | COORDINATION CATALYST | FINA RESEARCH, S.A. (BE) | 2002-06-18 | — | — | US | disclosed |
| EP-1010709-A1 | Metallocene compound and its use for polyolefin production | FINA RESEARCH S.A. (BE) | 2000-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133034-A1 | Polyolefin production | SRRM2, CSE1L, CACNA1A | NISCH 3608/4885 |
| US-20020120161-A1 | Polyolefin production | SRRM2, CSE1L, CACNA1A | NISCH 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.