Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319084 | 0.80 | TDP1 (0.51) | TDP1LMNAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL30699961 | 0.78 | CA1 (0.54) | TDP1GAALMNAKDM4EHSD17B10 | |
| SCHEMBL5572753 | 0.77 | SMN1; SMN2 (0.55) | LMNAKDM4EHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL5573302 | 0.77 | KMT2A (0.47) | TDP1GAALMNAKDM4EHSD17B10 | |
| SCHEMBL5496683 | 0.75 | LMNA (0.61) | TDP1GAALMNAKDM4EHSD17B10 | |
| SCHEMBL5496678 | 0.75 | LMNA (0.61) | TDP1GAALMNAKDM4EHSD17B10 | |
| SCHEMBL5569684 | 0.74 | STAT3 (0.50) | TDP1TAS2R14LMNAKDM4EHSD17B10 | |
| SCHEMBL4325972 | 0.73 | ACACB (0.66) | TDP1LMNASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL5573170 | 0.73 | TACR1 (0.54) | LMNAKDM4EHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL3858034 | 0.73 | MAPK1 (0.48) | TDP1LMNAKDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559127-B1 | Intercellular adhesion mediated by VLA-4 and other cell surface receptors is associated with a number of inflammatory responses | ATHENA NEUROSCIENCES, INC. | 2003-05-06 | — | — | US | disclosed |