SCHEMBL7169446

SCHEMBL7169446

Cc1c(N)cc(C(C)C)cc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
GAA P10253 3/20 0.48
HIF1A Q16665 2/20 0.48
ALOX12 P18054 1/20 0.48
HTT P42858 1/20 0.48
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
PIK3CA P42336 1/20 0.39
LMNA P02545 1/20 0.36
CD44 P16070 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TRPA1 O75762 1/20 0.34
PTGS1 P23219 1/20 0.34
CACNA1C Q13936 1/20 0.34
FABP3 P05413 2/20 0.33
FABP4 P15090 2/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22962176 0.87 ALDH1A1 (0.43) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL27494176 0.84 ALDH1A1 (0.55) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL1824775 0.84 ALDH1A1 (0.41) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL11440368 0.80 ALDH1A1 (0.38) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL29199950 0.78 ALDH1A1 (0.48) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL10342100 0.77 ALDH1A1 (0.43) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL8747660 0.76 FABP3 (0.46) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL25599237 0.76 ALDH1A1 (0.39) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL11864455 0.76 ALDH1A1 (0.58) ALDH1A1GAAHIF1AALOX12HTT
SCHEMBL22927069 0.74 ALDH1A1 (0.32) ALDH1A1GAAHIF1AALOX12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6552100-B2 Exposure to infrared radiation THE DOW CHEMICAL COMPANY 2003-04-22 US disclosed
US-6399206-B1 POLYUREAS OR POLYUETHANES AS PAINTS THE DOW CHEMICAL COMPANY 2002-06-04 US disclosed
US-20010041754-A1 Postcure treatment for reaction injection molded polyurethanes DOW CHEMICAL COMPANY, THE 2001-11-15 US disclosed
EP-0966348-B1 POSTCURE TREATMENT FOR REACTION INJECTION MOLDED POLYURETHANES DOW CHEMICAL CO (US) 2001-11-14 EP disclosed
US-6265464-B1 EXPOSURE TO INFRARED ENERGY THE DOW CHEMICAL COMPANY 2001-07-24 US disclosed
EP-0966348-A1 POSTCURE TREATMENT FOR REACTION INJECTION MOLDED POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1999-12-29 EP disclosed
US-5830541-A POLYURETHANE, POLYUREAS BLENDS ARE ELECTROSTATICALLY PAINTED THE DOW CHEMICAL COMPANY (US) 1998-11-03 US disclosed
WO-1998041387-A1 POSTCURE TREATMENT FOR REACTION INJECTION MOLDED POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1998-09-24 WO disclosed
EP-0662867-B1 ELECTROSTATICALLY PAINTED POLYMERS AND A PROCESS FOR MAKING SAME DOW CHEMICAL CO (US) 1998-08-26 EP disclosed
EP-0662867-A1 ELECTROSTATICALLY PAINTED POLYMERS AND A PROCESS FOR MAKING SAME THE DOW CHEMICAL COMPANY (US) 1995-07-19 EP disclosed
WO-1994007612-A1 ELECTROSTATICALLY PAINTED POLYMERS AND A PROCESS FOR MAKING SAME THE DOW CHEMICAL COMPANY (US) 1994-04-14 WO disclosed