SCHEMBL8747660

SCHEMBL8747660

Cc1c(N)cc(C(C)C)cc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.46
FABP4 P15090 2/20 0.46
FABP5 Q01469 1/20 0.46
ALDH1A1 P00352 8/20 0.39
GAA P10253 3/20 0.39
ALOX12 P18054 1/20 0.39
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
BRD4 O60885 1/20 0.34
TP53 P04637 1/20 0.34
CREBBP Q92793 1/20 0.34
TTR P02766 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
CASP6 P55212 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9284940 0.77 BRD4 (0.37) ALDH1A1GAAHTTBRD4TP53
SCHEMBL11038082 0.77 ALDH1A1 (0.47) ALDH1A1GAABRD4TP53CREBBP
SCHEMBL9680119 0.77 TDP1 (0.47) ALDH1A1GAABRD4TP53CREBBP
SCHEMBL1365450 0.76 ALDH1A1 (0.48) FABP3FABP4FABP5ALDH1A1GAA
SCHEMBL7169446 0.76 ALDH1A1 (0.48) FABP3FABP4FABP5ALDH1A1GAA
SCHEMBL9337500 0.76 ALDH1A1 (0.49) ALDH1A1GAAHTTBRD4TP53
SCHEMBL17262959 0.76 BRD4 (0.40) ALDH1A1GAAHIF1ABRD4TP53
SCHEMBL8369558 0.75 FABP3 (0.53) FABP3FABP4FABP5ALDH1A1ALOX12
SCHEMBL10597827 0.74 CA1 (0.39) ALDH1A1GAABRD4TP53CREBBP
SCHEMBL27494176 0.71 ALDH1A1 (0.55) ALDH1A1GAAALOX12HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed