SCHEMBL7169609

SCHEMBL7169609

Cc1cc(F)c(N)nc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KHK P50053 1/20 0.39
NOS3 P29474 4/20 0.39
NOS1 P29475 4/20 0.39
NOS2 P35228 4/20 0.39
KDM4E B2RXH2 1/20 0.33
TERT O14746 1/20 0.33
NQO1 P15559 1/20 0.32
ILK Q13418 1/20 0.32
IDO1 P14902 1/20 0.31
NCF1 P14598 1/20 0.31
MPL P40238 1/20 0.31
CYP3A4 P08684 3/20 0.31
TSHR P16473 3/20 0.31
ALDH1A1 P00352 2/20 0.31
TP53 P04637 2/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18033375 0.83 NOS3 (0.38) KHKNOS3NOS1NOS2KDM4E
SCHEMBL20355266 0.83 KHK (0.38) KHKNOS3NOS1NOS2KDM4E
SCHEMBL18697135 0.83 NOS3 (0.39) KHKNOS3NOS1NOS2KDM4E
SCHEMBL10144932 0.83 NOS3 (0.38) KHKNOS3NOS1NOS2KDM4E
SCHEMBL1565794 0.81 KHK (0.46) KHKKDM4ENQO1NCF1ALDH1A1
SCHEMBL3220307 0.81 NOS3 (0.48) NOS3NOS1NOS2KDM4ETERT
SCHEMBL18554888 0.79 NOS3 (0.35) NOS3NOS1NOS2KDM4ETERT
SCHEMBL30052259 0.79 NOS3 (0.35) NOS3NOS1NOS2KDM4ETERT
Hydrochloric Acid SCHEMBL21752363 0.78 NOS3 (0.34) NOS3NOS1NOS2KDM4ETERT
SCHEMBL29295851 0.76 POLB (0.34) KHKNOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116922004-A Manufacturing method of non-stick pan with wear-resistant antibacterial coating 宁波市金象厨具有限公司 2023-10-24 CN claimed
CN-116922004-A Manufacturing method of non-stick pan with wear-resistant antibacterial coating 宁波市金象厨具有限公司 2023-10-24 CN disclosed
CN-1196683-C Amino-compound YUNAGA PHARMACEUTICAL CO LTD (JP) 2005-04-13 CN disclosed
EP-0952151-B1 Intermediates for use in preparing novel pyridonecarboxylic acid derivatives or their salts WAKUNAGA PHARMA CO LTD (JP) 2003-05-28 EP disclosed
CN-1105715-C Novel pyridonecarboxylic acid derivative or salt thereof, and antibacterial agent containing same as active ingredient WAKUNAGA PHARMA CO LTD (JP) 2003-04-16 CN disclosed
EP-0911327-B1 NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR THEIR SALTS AND ANTIBACTERIAL AGENT COMPRISING THE SAME AS THE ACTIVE INGREDIENT WAKUNAGA PHARMA CO LTD (JP) 2001-12-05 EP disclosed
US-6156903-A Pyridonecarboxylic acid derivatives or their salts, and antibacterial agents containing the same as their effective components WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2000-12-05 US disclosed
US-6133284-A EXCELLENT BACTERICIDAL PROPERTIES AND ORAL ABSORPTION; INFECTIONS FROM GRAMNEGATIVE AND -POSITIVE BACTERIA; INTESTINAL ABSORPTION, METABOLIC STABILITY; SIDE EFFECT REDUCTION; NONPHOTOTOXICITY AND NONCYTOTOXICITY WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2000-10-17 US disclosed
CN-1258672-A Amino-compound YUNAGA PHARMACEUTICAL CO LTD (JP) 2000-07-05 CN disclosed
CN-1258674-A Pyrone carboxylic acid derivate or its salt and antibiotic with the same as effective component YUNAGA PHARMACEUTICAL CO LTD (JP) 2000-07-05 CN disclosed
EP-0992501-A2 Pyridonecarboxylic acid derivatives as antibacterial agents WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2000-04-12 EP disclosed
US-5998436-A Pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising the same as the active ingredient WAKUNAGA PHARMACEUTICALS CO., LTD. (JP) 1999-12-07 US disclosed
EP-0952151-A2 Intermediates for use in preparing novel pyridonecarboxylic acid derivatives or their salts WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1999-10-27 EP disclosed
EP-0911327-A1 NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR THEIR SALTS AND ANTIBACTERIAL AGENT COMPRISING THE SAME AS THE ACTIVE INGREDIENT WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1999-04-28 EP disclosed
CN-1201459-A Novel pyridonecarboxylic acid derivative or salt thereof, and antibacterial agent containing same as active ingredient WAKUNAGA PHARMA CO LTD (JP) 1998-12-09 CN disclosed