Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979054 | 0.83 | KHK (0.39) | NOS3NOS1NOS2KHKLMNA | |
| SCHEMBL7169609 | 0.83 | KHK (0.39) | NOS3NOS1NOS2KHKLMNA | |
| SCHEMBL20355266 | 0.81 | KHK (0.38) | NOS3NOS1NOS2KHKKDM4E | |
| SCHEMBL10144932 | 0.81 | NOS3 (0.38) | NOS3NOS1NOS2KHKLMNA | |
| SCHEMBL21047969 | 0.77 | LMNA (0.41) | KHKLMNAALDH1A1KMT2ATERT | |
| SCHEMBL16501095 | 0.77 | KHK (0.44) | KHKLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL26688044 | 0.77 | KHK (0.36) | KHKLMNA | |
| SCHEMBL4331730 | 0.77 | NOS3 (0.33) | NOS3NOS1NOS2CYP1A2SMN1; SMN2 | |
| SCHEMBL9753602 | 0.77 | NOS3 (0.44) | NOS3NOS1NOS2CYP1A2LMNA | |
| SCHEMBL28292898 | 0.77 | NOS3 (0.44) | NOS3NOS1NOS2CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389751-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| EP-4265607-A1 | AMINOPYRIDINE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2023-10-25 | — | — | EP | disclosed |
| EP-3766876-B1 | PHARMACEUTICAL FORMULATION CONTAINING A QUINOLONE DERIVATIVE | MELINTA SUBSIDIARY CORP (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-2346855-B1 | PROCESS FOR MAKING QUINOLONE COMPOUNDS | MELINTA THERAPEUTICS INC (US) | 2017-04-05 | — | — | EP | disclosed |