Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170156 | 1.00 | CYP19A1 (0.52) | CYP19A1SIGMAR1HTR1AHTR6CYP26A1 | |
| SCHEMBL7244217 | 0.81 | CYP26A1 (0.38) | CYP19A1SIGMAR1HTR1ACYP26A1HPGD | |
| SCHEMBL7244213 | 0.81 | CYP26A1 (0.38) | CYP19A1SIGMAR1HTR1ACYP26A1HPGD | |
| SCHEMBL28733987 | 0.78 | CYP19A1 (0.80) | CYP19A1SIGMAR1HTR1ACYP26A1DDB1 | |
| SCHEMBL3761876 | 0.78 | CYP19A1 (0.80) | CYP19A1SIGMAR1HTR1ACYP26A1DDB1 | |
| SCHEMBL30275056 | 0.78 | CYP19A1 (0.80) | CYP19A1SIGMAR1HTR1ACYP26A1DDB1 | |
| SCHEMBL7242889 | 0.77 | ALDH1A1 (0.46) | CYP19A1CYP26A1HPGDHTR2C | |
| SCHEMBL7242893 | 0.77 | ALDH1A1 (0.46) | CYP19A1CYP26A1HPGDHTR2C | |
| SCHEMBL31374595 | 0.73 | SMN1; SMN2 (0.39) | CYP19A1HPGDL3MBTL1HTR2C | |
| SCHEMBL8886079 | 0.73 | CYP19A1 (0.45) | CYP19A1SIGMAR1DDB1CRBNGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | GOLDSTEIN STEVEN WAYNE (US) | 2003-10-09 | — | — | US | disclosed |
| US-6576632-B1 | Such as 3'-((Benzyl-(2-benzyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-carbamoyl)-methyl)-biphenyl-3-carboxylic acid | PFIZER INC | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | CCNA1, CCNE1, CCND1 | CYP19A1 2314/4885SIGMAR1 2522/4885HTR1A 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.