Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 5/20 | 0.40 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242893 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HTR2CCYP24A1CYP27A1CYP26A1 | |
| SCHEMBL7244213 | 0.82 | CYP26A1 (0.38) | ALDH1A1HTR2CCYP24A1CYP27A1CYP26A1 | |
| SCHEMBL7244217 | 0.82 | CYP26A1 (0.38) | ALDH1A1HTR2CCYP24A1CYP27A1CYP26A1 | |
| SCHEMBL7249428 | 0.81 | CYP24A1 (0.59) | HTR2CCYP24A1CYP27A1CYP26A1CYP2D6 | |
| SCHEMBL15874612 | 0.81 | CYP24A1 (0.59) | HTR2CCYP24A1CYP27A1CYP26A1CYP2D6 | |
| SCHEMBL7170156 | 0.77 | CYP19A1 (0.52) | HTR2CCYP26A1HPGDCYP19A1 | |
| SCHEMBL7170153 | 0.77 | CYP19A1 (0.52) | HTR2CCYP26A1HPGDCYP19A1 | |
| SCHEMBL31374595 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1HTR2CHPGDLMNASMN1; SMN2 | |
| SCHEMBL6181741 | 0.71 | HPGD (0.41) | ALDH1A1HPGDLMNAMAPTCYP19A1 | |
| SCHEMBL28733986 | 0.70 | CYP24A1 (0.56) | ALDH1A1HTR2CCYP24A1CYP27A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | GOLDSTEIN STEVEN WAYNE (US) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | CCNA1, CCNE1, CCND1 | ALDH1A1 1215/4885HTR2C 4716/4885CYP24A1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.