SCHEMBL7170235

SCHEMBL7170235

CCCCCCCCC=CCCCCCCCCO[Si](OCCCCCCCCC=CCCCCCCCC)(OCCCCCCCCC=CCCCCCCCC)OCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.52
LPAR3 Q9UBY5 3/20 0.52
LPAR1 Q92633 2/20 0.52
FAAH O00519 2/20 0.50
TRPV1 Q8NER1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7170228 1.00 LPAR2 (0.52) LPAR2LPAR3LPAR1FAAHTRPV1
Oleyl Alcohol SCHEMBL7625014 0.91 LPAR2 (0.49) LPAR2LPAR3LPAR1TRPV1
Oleyl Alcohol SCHEMBL7625020 0.91 LPAR2 (0.49) LPAR2LPAR3LPAR1TRPV1
SCHEMBL77168 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL11592491 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL2397962 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL7172026 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL9119727 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL11572901 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL766409 0.86 THRB (0.47) LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216504-A1 Biomimetic silicone elastomers XIOMATERIA LIMITED (IE) 2003-11-20 US disclosed
EP-1244738-B1 BIOMIMETIC SILICONE ELASTOMERS XIOMATERIA LTD (GB) 2003-06-11 EP disclosed
WO-2002090436-A2 BIOACTIVE BIOMIMETIC ELASTOMERS XIOMATERIA LIMITED (GB) 2002-11-14 WO disclosed
EP-1244738-A1 BIOMIMETIC SILICONE ELASTOMERS Xiomateria Limited (GB) 2002-10-02 EP disclosed
WO-2001034695-A1 BIOMIMETIC SILICONE ELASTOMERS XIOMATERIA LIMITED (GB) 2001-05-17 WO disclosed