SCHEMBL7170228

SCHEMBL7170228

CCCCCCCC/C=C\CCCCCCCCO[Si](OCCCCCCCC/C=C\CCCCCCCC)(OCCCCCCCC/C=C\CCCCCCCC)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.52
LPAR3 Q9UBY5 3/20 0.52
LPAR1 Q92633 2/20 0.52
FAAH O00519 2/20 0.50
TRPV1 Q8NER1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7170235 1.00 LPAR2 (0.52) LPAR2LPAR3LPAR1FAAHTRPV1
Oleyl Alcohol SCHEMBL7625014 0.91 LPAR2 (0.49) LPAR2LPAR3LPAR1TRPV1
Oleyl Alcohol SCHEMBL7625020 0.91 LPAR2 (0.49) LPAR2LPAR3LPAR1TRPV1
SCHEMBL77168 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL11592491 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL2397962 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL7172026 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL9119727 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL11572901 0.86 THRB (0.47) LPAR2LPAR3LPAR1
SCHEMBL766409 0.86 THRB (0.47) LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590151-B2 Silanes and curable compositions comprising said silanes HENKEL AG & CO. KGAA (DE) 2020-03-17 US disclosed
US-20190202844-A1 Silanes and Curable Compositions Comprising Said Silanes HENKEL AG & CO. KGAA (DE) 2019-07-04 US disclosed
EP-3293188-B1 SILANES AND CURABLE COMPOSITIONS COMPRISING SAID SILANES HENKEL AG & CO KGAA (DE) 2019-04-10 EP disclosed
WO-2018050503-A1 SILANES AND CURABLE COMPOSITIONS COMPRISING SAID SILANES HENKEL AG & CO. KGAA (DE) 2018-03-22 WO disclosed
EP-3293188-A1 SILANES AND CURABLE COMPOSITIONS COMPRISING SAID SILANES Henkel AG & Co. KGaA (DE) 2018-03-14 EP disclosed
US-20030216504-A1 Biomimetic silicone elastomers XIOMATERIA LIMITED (IE) 2003-11-20 US disclosed
EP-1244738-B1 BIOMIMETIC SILICONE ELASTOMERS XIOMATERIA LTD (GB) 2003-06-11 EP disclosed
WO-2002090436-A2 BIOACTIVE BIOMIMETIC ELASTOMERS XIOMATERIA LIMITED (GB) 2002-11-14 WO disclosed
EP-1244738-A1 BIOMIMETIC SILICONE ELASTOMERS Xiomateria Limited (GB) 2002-10-02 EP disclosed
WO-2001034695-A1 BIOMIMETIC SILICONE ELASTOMERS XIOMATERIA LIMITED (GB) 2001-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10590151-B2 Silanes and curable compositions comprising said silanes CLNS1A, RCC1, RIF1 LPAR2 2802/4885LPAR3 3307/4885LPAR1 1860/4885
US-20190202844-A1 Silanes and Curable Compositions Comprising Said Silanes CLNS1A, RCC1, RIF1 LPAR2 2802/4885LPAR3 3307/4885LPAR1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.