Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 8/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27245989 | 0.85 | PTPN11 (1.00) | PTPN11PTPN1PTPN6S1PR3 | |
| SCHEMBL3184382 | 0.85 | PTPN11 (0.55) | PTPN11IDO1 | |
| SCHEMBL8181779 | 0.82 | PTPN11 (0.68) | PTPN11PTPN1PTPN6 | |
| SCHEMBL7170404 | 0.82 | PTPN11 (0.80) | PTPN11PTPN1PTPN6S1PR3 | |
| SCHEMBL8178709 | 0.80 | CREBBP (0.60) | PTPN11 | |
| SCHEMBL7172420 | 0.80 | AKR1C3 (0.53) | PTPN11PTPN1PLK1S1PR3 | |
| SCHEMBL7166121 | 0.78 | PTPN11 (0.73) | PTPN11PTPN1PTPN6S1PR3 | |
| SCHEMBL11482525 | 0.77 | KMT2A (0.64) | PTPN1 | |
| SCHEMBL14625066 | 0.77 | KMT2A (0.64) | PTPN1 | |
| SCHEMBL7952997 | 0.77 | KMT2A (0.64) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569504-B1 | Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) | DISPLAYTECH, INC. | 2003-05-27 | — | — | US | disclosed |
| US-6139771-A | USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS | DISPLAYTECH, INC. (US) | 2000-10-31 | — | — | US | disclosed |