Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL7821806 | 0.94 | CREBBP (0.55) | CREBBPALDH1A1HPGDPTPN11MEN1 | |
| SCHEMBL8181779 | 0.91 | PTPN11 (0.68) | CREBBPALDH1A1HPGDPTPN11MEN1 | |
| SCHEMBL11582978 | 0.85 | EPHX1 (0.52) | SMN1; SMN2TP53TSHR | |
| SCHEMBL8484560 | 0.85 | EPHX1 (0.52) | SMN1; SMN2TP53TSHR | |
| SCHEMBL14625062 | 0.85 | GAA (0.59) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7821811 | 0.84 | CREBBP (0.45) | CREBBPALDH1A1HPGDPTPN11MEN1 | |
| SCHEMBL8178705 | 0.83 | ALDH1A1 (0.45) | CREBBPALDH1A1HPGDPTPN11MEN1 | |
| SCHEMBL8178707 | 0.83 | ALDH1A1 (0.45) | CREBBPALDH1A1HPGDPTPN11MEN1 | |
| SCHEMBL2308150 | 0.83 | ALDH1A1 (0.61) | CREBBPALDH1A1HPGDPTPN11TP53 | |
| SCHEMBL1199847 | 0.81 | ALDH1A1 (0.69) | ALDH1A1HPGDPTPN11TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |