Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 9/20 | 0.33 |
| ▸ | NPY1R | P25929 | 6/20 | 0.33 |
| ▸ | NPY2R | P49146 | 4/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170054 | 1.00 | PLG (0.35) | PLGF10PLAUKLKB1NPY4R | |
| SCHEMBL7165122 | 0.92 | PLG (0.35) | PLGF10PLAUKLKB1 | |
| SCHEMBL7168204 | 0.87 | PLG (0.34) | PLGF10PLAUKLKB1NPY4R | |
| SCHEMBL7171608 | 0.87 | PLG (0.34) | PLGF10PLAUKLKB1NPY4R | |
| SCHEMBL7163853 | 0.82 | PLG (0.34) | PLGF10PLAUKLKB1 | |
| SCHEMBL8526347 | 0.79 | PLG (0.40) | PLGF10PLAUKLKB1NPY4R | |
| SCHEMBL7744390 | 0.78 | PLG (0.40) | PLGF10PLAUKLKB1NPY4R | |
| SCHEMBL7170495 | 0.77 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7170375 | 0.77 | PLG (0.43) | PLGF10PLAUKLKB1NPY4R | |
| SCHEMBL7170050 | 0.77 | PLG (0.43) | PLGF10PLAUKLKB1NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789578-B1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0789578-A4 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-0789578-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014857-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1996-05-23 | — | — | WO | disclosed |