Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.38 |
| ▸ | NPY1R | P25929 | 9/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.38 |
| ▸ | NPY2R | P49146 | 5/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166802 | 0.88 | NPY4R (0.37) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7170368 | 0.86 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7168920 | 0.84 | NPY4R (0.35) | NPY4RNPY1RNPY5RNPY2REPHX2 | |
| Hydrochloric Acid SCHEMBL11142424 | 0.78 | PLAU (0.39) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7170054 | 0.77 | PLG (0.35) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7170382 | 0.77 | PLG (0.35) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL11142106 | 0.75 | LARS1 (0.40) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7167389 | 0.74 | AVPR1B (0.35) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL11140588 | 0.72 | NPY5R (0.35) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7165148 | 0.72 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789578-B1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0789578-A4 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-0789578-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014857-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1996-05-23 | — | — | WO | disclosed |