Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170489 | 0.79 | RXFP1 (0.57) | RXFP1KMT2ATSHRLMNAHTT | |
| SCHEMBL3099603 | 0.75 | RXFP1 (1.00) | RXFP1KMT2ATSHRLMNASMN1; SMN2 | |
| SCHEMBL29376542 | 0.72 | RXFP1 (0.72) | RXFP1KMT2ATSHRLMNAHTT | |
| SCHEMBL8577754 | 0.71 | RXFP1 (0.63) | RXFP1KMT2ATSHRLMNAHTT | |
| Bamifylline SCHEMBL219043 | 0.71 | RXFP1 (0.60) | RXFP1KMT2ATSHRLMNAHTT | |
| SCHEMBL8683232 | 0.70 | RXFP1 (0.58) | RXFP1KMT2ATSHRLMNAHTT | |
| Bamifylline SCHEMBL637064 | 0.70 | RXFP1 (0.58) | RXFP1KMT2ATSHRLMNAHTT | |
| SCHEMBL8373802 | 0.69 | RXFP1 (0.72) | RXFP1KMT2ATSHRLMNAHTT | |
| SCHEMBL8373801 | 0.69 | RXFP1 (0.72) | RXFP1KMT2ATSHRLMNAHTT | |
| Bamifylline SCHEMBL1648640 | 0.69 | RXFP1 (0.57) | RXFP1KMT2ATSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103675-A2 | COMBINATION TREATMENTS FOR PURINOCEPTOR-RELATED DISORDERS | ENDACEA, INC. (US) | 2003-12-18 | — | — | WO | disclosed |