Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676460 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDCA12 | |
| SCHEMBL1837900 | 0.84 | ESR1 (0.42) | ALDH1A1KDM4EHSD17B10LMNANPC1 | |
| SCHEMBL1841418 | 0.84 | MAOB (0.50) | ALDH1A1KDM4EHPGDLMNANPC1 | |
| SCHEMBL27667660 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDCA12 | |
| SCHEMBL27654150 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10HPGDCA12 | |
| SCHEMBL18869371 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10HPGDCA12 | |
| SCHEMBL29501710 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1KDM4ELMNANQO1IDO1 | |
| SCHEMBL6990892 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDCA12 | |
| SCHEMBL4783142 | 0.76 | TYR (0.54) | KDM4ELMNAPOLBL3MBTL1CYBB | |
| SCHEMBL13318414 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053342-A1 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-03-01 | — | — | US | disclosed |
| US-8058469-B2 | Method for making carbamates, ureas and isocyanates | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-11-15 | — | — | US | disclosed |
| EP-2362867-A2 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | SABIC Innovative Plastics IP B.V. (NL) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010062490-A2 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-06-03 | — | — | WO | disclosed |
| US-20100113819-A1 | Method for Making Carbamates, Ureas and Isocyanates | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113819-A1 | Method for Making Carbamates, Ureas and Isocyanates | CPS1, ALKBH3, KDM8 | ALDH1A1 2313/4885KDM4E 73/4885HSD17B10 1456/4885 |
| US-20120053342-A1 | METHOD FOR MAKING CARBAMATES, UREAS AND ISOCYANATES | CPS1, ALKBH3, IDH3A | ALDH1A1 2343/4885KDM4E 80/4885HSD17B10 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.