SCHEMBL676460

SCHEMBL676460

Cc1cccc(COC(=O)OCc2cccc(C)c2O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 3/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 1/20 0.42
TRPA1 O75762 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
EGFR P00533 1/20 0.41
ERBB2 P04626 1/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
PTGER1 P34995 2/20 0.40
PTGER4 P35408 2/20 0.40
PTGER3 P43115 2/20 0.40
PTGER2 P43116 2/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717175 0.86 ALDH1A1 (0.43) ALDH1A1KDM4EHSD17B10HPGDLMNA
SCHEMBL27667660 0.84 ALDH1A1 (0.53) ALDH1A1KDM4EHSD17B10HPGDLMNA
SCHEMBL17942298 0.83 GABRA1 (0.65) ALDH1A1GABRA1GABRB2CA12CA1
SCHEMBL6552314 0.83 ESR1 (0.45) ALDH1A1KDM4EHSD17B10LMNATRPA1
SCHEMBL8211971 0.82 MAOB (0.53) ALDH1A1KDM4EHPGDLMNANPC1
SCHEMBL27654150 0.82 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10HPGDLMNA
SCHEMBL18869371 0.80 ALDH1A1 (0.54) ALDH1A1KDM4EHSD17B10HPGDLMNA
SCHEMBL4783142 0.79 TYR (0.54) KDM4ELMNAL3MBTL1CYBBGAA
SCHEMBL2887703 0.79 IAPP (0.49) GABRA1GABRB2CYP4F2CYP4A11CYBB
SCHEMBL13318414 0.79 ALDH1A1 (0.52) ALDH1A1KDM4EHSD17B10HPGDTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155802-B1 POLYCARBONATE-POLY(ALKYLENE OXIDE) COPOLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-03-06 EP claimed
EP-1973960-B1 POLYESTER OLIGOMERS, METHODS OF MAKING, AND THERMOSETTING COMPOSITIONS FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2011-03-02 EP claimed
US-7687595-B2 Sulfonated telechelic polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-30 US claimed
EP-2155802-A1 POLYCARBONATE-POLY(ALKYLENE OXIDE) COPOLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2010-02-24 EP claimed
WO-2009020966-A1 SULFONATED TELECHELIC POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-02-12 WO claimed
WO-2009020967-A1 ACTIVATED ESTERS FOR SYNTHESIS OF SULFONATED TELECHELIC POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-02-12 WO claimed
WO-2008157328-A1 POLYCARBONATE-POLY(ALKYLENE OXIDE) COPOLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-12-24 WO claimed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US claimed
EP-1973960-A2 POLYESTER OLIGOMERS, METHODS OF MAKING, AND THERMOSETTING COMPOSITIONS FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-10-01 EP claimed
WO-2007081539-A2 POLYESTER OLIGOMERS, METHODS OF MAKING, AND THERMOSETTING COMPOSITIONS FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-07-19 WO claimed
US-20070155946-A1 Polyester oligomers, methods of making, and thermosetting compositions formed therefrom CITIBANK, N.A., AS COLLATERAL AGENT 2007-07-05 US claimed
EP-3822299-B1 BIO-BASED POLYCARBONATE ESTER RESIN FOR EYEGLASS FRAME SK CHEMICALS CO LTD (KR) 2026-02-18 EP disclosed
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio COVESTRO DEUTSCHLAND AG (DE) 2026-01-27 US disclosed
US-12516152-B2 Polyester carbonates having a defined proportion of ester groups COVESTRO DEUTSCHLAND AG (DE) 2026-01-06 US disclosed
US-12473397-B2 Polyester carbonates from aliphatic diacids and aliphatic diols, and process for the production thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-11-18 US disclosed
WO-2005085319-A1 LIQUID CRYSTAL POLYCARBONATES AND METHODS OF PREPARING SAME GENERAL ELECTRIC COMPANY (US) 2005-09-15 WO disclosed
EP-1458786-A1 PROCESS FOR PREPARING BRANCHED AROMATIC POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-09-22 EP disclosed
EP-1414888-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
WO-2003050161-A1 PROCESS FOR PREPARING BRANCHED AROMATIC POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-06-19 WO disclosed
WO-2003010220-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio HSD11B2, HSD11B1, HSD3B1 ALDH1A1 958/4885KDM4E 3184/4885HSD17B10 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.