Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607572 | 0.83 | FFAR1 (0.52) | MAOBFFAR1SPHK2SPHK1NR4A2 | |
| SCHEMBL9270379 | 0.82 | FFAR1 (0.64) | MAOBFFAR1SPHK2SPHK1HTT | |
| SCHEMBL811204 | 0.82 | MAOB (0.55) | MAOBFFAR1SPHK2SPHK1NR4A2 | |
| SCHEMBL8596853 | 0.82 | DHFR (0.47) | MAOBDHFRDCPSNR4A2NPC1 | |
| SCHEMBL27414049 | 0.79 | HTR6 (0.43) | MAOBFFAR1DHFRDCPSNR4A2 | |
| SCHEMBL15331303 | 0.78 | FFAR1 (0.48) | MAOBFFAR1SPHK2SPHK1NR4A2 | |
| SCHEMBL28591722 | 0.78 | NPC1 (0.63) | MAOBFFAR1SPHK2SPHK1NPC1 | |
| SCHEMBL4030554 | 0.78 | NR4A2 (0.67) | FFAR1SPHK2SPHK1NR4A2NPC1 | |
| SCHEMBL9076409 | 0.78 | MAPT (0.49) | FFAR1DHFRDCPSNR4A2NPC1 | |
| SCHEMBL1155388 | 0.78 | DHFR (0.50) | MAOBDHFRDCPSNR4A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653258-B1 | Pyridinyl-substituted- methyl 3-methoxy-2-phenylacrylate derivatives; agricultural miticides and nematocides | SYNGENTA LIMITED (GB) | 2003-11-25 | — | — | US | disclosed |
| EP-0278595-B2 | Fungicides | ZENECA LTD (GB) | 2000-01-12 | — | — | EP | disclosed |
| US-5438059-A | Derivatives of propenoic acid; stereoisomers; applying to plants | ZENECA LIMITED (GB) | 1995-08-01 | — | — | US | disclosed |
| EP-0472224-B1 | Fungicides | ZENECA LTD (GB) | 1994-04-27 | — | — | EP | disclosed |
| EP-0472224-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-02-26 | — | — | EP | disclosed |
| US-5021581-A | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| EP-0278595-A2 | Fungicides | ZENECA LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |