Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695193 | 0.86 | ALDH1A1 (0.53) | GFERALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL23922857 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HTTSMN1; SMN2MAPTTSHR | |
| SCHEMBL6695190 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTTSHRKDM4E | |
| SCHEMBL1646672 | 0.80 | POLB (0.57) | L3MBTL1 | |
| SCHEMBL20241827 | 0.79 | ALDH1A1 (0.47) | GFERALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL17157069 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1HTTSMN1; SMN2TRPV6 | |
| SCHEMBL31670698 | 0.78 | SIGMAR1 (0.55) | ALDH1A1HTTSMN1; SMN2MAPTTRPV6 | |
| SCHEMBL8045561 | 0.78 | SIGMAR1 (0.55) | ALDH1A1HTTSMN1; SMN2MAPTTRPV6 | |
| SCHEMBL12536025 | 0.77 | CYP2D6 (0.54) | ALDH1A1HTTSMN1; SMN2MAPTTSHR | |
| SCHEMBL7263869 | 0.77 | ALDH1A1 (0.46) | GFERALDH1A1HTTMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101994-A1 | FUSED BICYCLIC AROMATIC COMPOUNDS THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-11 | — | — | WO | disclosed |