SCHEMBL7173183

SCHEMBL7173183

O=c1[nH]c(NCCC(O)O)nc2nc[nH]c12

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 0.66
GDA Q9Y2T3 1/20 0.56
PNP P00491 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5664381 0.92 XDH (0.70) XDHGDA
SCHEMBL7617811 0.88 XDH (0.62) XDHGDA
SCHEMBL5935074 0.87 XDH (0.78) XDHGDAPNP
SCHEMBL28997136 0.86 XDH (0.66) XDHGDA
SCHEMBL16093685 0.85 XDH (0.64) XDHGDA
SCHEMBL8864963 0.85 XDH (0.54) XDHGDA
SCHEMBL6751934 0.85 XDH (0.71) XDHGDAPNP
SCHEMBL30862132 0.83 XDH (0.58) XDHGDA
SCHEMBL667798 0.82 XDH (0.84) XDHGDA
SCHEMBL9806979 0.82 XDH (0.71) XDHGDAPNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6573247-B1 Prophylaxis or treatment of varicella-zoster virus or cytomegalo virus infections UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2003-06-03 US disclosed
EP-0980377-B1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIV CARDIFF (GB) 2002-07-31 EP disclosed
EP-0980377-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES University College Cardiff Consultants Limited (GB) 2000-02-23 EP disclosed
WO-1998049177-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 1998-11-05 WO disclosed