Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 7/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160310 | 0.72 | LMNA (0.46) | LMNACYP2C19FDPSLAP3KDM4E | |
| SCHEMBL28568807 | 0.71 | SMPD1 (0.37) | FDPSLAP3LPAR3LPAR1LPAR2 | |
| SCHEMBL3244386 | 0.71 | LMNA (0.56) | LMNACYP2C19FDPSKDM4ETSHR | |
| SCHEMBL8154047 | 0.68 | LMNA (0.38) | LMNACYP2C19KDM4ETSHRTDP1 | |
| Phosphoric Acid SCHEMBL29565136 | 0.68 | FDPS (0.42) | LMNACYP2C19FDPSLAP3KDM4E | |
| SCHEMBL3860656 | 0.67 | LMNA (0.47) | LMNACYP2C19KDM4ETSHRTDP1 | |
| SCHEMBL8373119 | 0.66 | TSHR (0.41) | LMNACYP2C19FDPSLAP3KDM4E | |
| SCHEMBL8154048 | 0.66 | TSHR (0.41) | LMNACYP2C19FDPSLAP3KDM4E | |
| SCHEMBL8372978 | 0.66 | TSHR (0.41) | LMNACYP2C19FDPSLAP3KDM4E | |
| SCHEMBL28790839 | 0.65 | KDM4E (0.37) | LMNACYP2C19KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583182-B1 | Atomic numbers 21-30 are components of enzymes required for nucleic acid replication; substituted polyaza compounds inhibit cell replication by decreaseing bioavailability of iron or copper | CHELATOR LLC | 2003-06-24 | — | — | US | disclosed |