Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7176612 | 0.97 | MAPK1 (0.36) | MAPK1RAB9AHTTNPC1HPGD | |
| Hydrochloric Acid SCHEMBL7175589 | 0.97 | MAPK1 (0.36) | MAPK1RAB9AHTTNPC1HPGD | |
| Hydrochloric Acid SCHEMBL7176580 | 0.97 | MAPK1 (0.36) | MAPK1RAB9AHTTNPC1HPGD | |
| Hydrochloric Acid SCHEMBL7172230 | 0.97 | MAPK1 (0.36) | MAPK1RAB9AHTTNPC1HPGD | |
| Hydrochloric Acid SCHEMBL7179084 | 0.97 | MAPK1 (0.36) | MAPK1RAB9AHTTNPC1HPGD | |
| Hydrochloric Acid SCHEMBL7180919 | 0.93 | NOS2 (0.36) | HTTNOS2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7185415 | 0.91 | NOS2 (0.36) | HTTNOS2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7177918 | 0.91 | NOS2 (0.36) | HTTNOS2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7183835 | 0.91 | NOS2 (0.36) | HTTNOS2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7172334 | 0.91 | NOS2 (0.36) | HTTNOS2SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |