SCHEMBL7174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7188	0.93	LPAR1 (0.38)	ALDH1A1SMN1; SMN2MAPTABCC3ABCC4
	SCHEMBL7175	0.87	LPAR1 (0.38)	ALDH1A1SMN1; SMN2MAPTABCC3ABCC4
	SCHEMBL7241	0.84	LIPG (0.44)	SLCO1B1FAAHTSHR
	SCHEMBL1596	0.83	LPAR1 (0.52)	ALDH1A1SMN1; SMN2MAPTABCC3ABCC4
	SCHEMBL12091	0.81	TSHR (0.41)	ALDH1A1SMN1; SMN2MAPTLPAR1BRD4
	SCHEMBL6415	0.81	TP53 (0.40)	LPAR1FAAHTSHRTP53PDE4A
	SCHEMBL13720569	0.80	LPAR1 (0.44)	ALDH1A1SMN1; SMN2MAPTABCC3ABCC4
	SCHEMBL1991	0.79	LPAR1 (0.46)	ALDH1A1SMN1; SMN2MAPTABCC3ABCC4
	SCHEMBL6860	0.79	LPAR1 (0.40)	ALDH1A1SMN1; SMN2MAPTABCC3ABCC4
	SCHEMBL6888	0.79	FFAR1 (0.47)	SMN1; SMN2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.