Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875802 | 1.00 | OPRK1 (0.38) | OPRK1SOS1CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL717163 | 0.87 | HRH4 (0.41) | OPRK1SOS1HRH4 | |
| SCHEMBL15875828 | 0.87 | HRH4 (0.41) | OPRK1SOS1HRH4 | |
| SCHEMBL713421 | 0.87 | OPRK1 (0.40) | OPRK1PIK3CDHRH4 | |
| SCHEMBL15875847 | 0.87 | OPRK1 (0.40) | OPRK1PIK3CDHRH4 | |
| SCHEMBL716484 | 0.83 | MAPT (0.38) | OPRK1SOS1HRH4 | |
| SCHEMBL716483 | 0.83 | MAPT (0.38) | OPRK1SOS1HRH4 | |
| SCHEMBL15875794 | 0.82 | OPRK1 (0.40) | OPRK1SCN10A | |
| SCHEMBL714749 | 0.81 | OPRK1 (0.39) | OPRK1SCN10A | |
| SCHEMBL716736 | 0.80 | OPRK1 (0.41) | OPRK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | UCB PHARMA, S.A. (BE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | MAP3K15, PI4KA, MAP3K20 | OPRK1 416/4885SOS1 1414/4885CYP2C8 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.