Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.61 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | FLT1 | P17948 | 1/20 | 0.57 |
| ▸ | FLT4 | P35916 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15137067 | 0.92 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL31456323 | 0.91 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8731678 | 0.88 | PARP1 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9106376 | 0.88 | KMT2A (0.70) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11589747 | 0.88 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11064749 | 0.87 | PKM (0.67) | ALDH1A1PARP1KCNK3KCNK9KCNMA1 | |
| SCHEMBL14527269 | 0.86 | NPC1 (0.71) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL12218087 | 0.86 | ALDH1A1 (0.73) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6674303 | 0.85 | KDM4E (0.62) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5925632 | 0.84 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |